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Regular price $70.46
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NAD+ Complete

NAD+ Complete

BUNDLE & SAVE

NAD+ Complete

NAD+ Complete

Regular price $70.46
Regular price $70.46 Sale price $84.95
SAVE 17% Sold out

Renue By Science NAD+ Complete | 120 Liposomal NAD Supplement Capsules with NMN, NR & Trigonelline - 310mg NMN & 160mg NAD per Serving | Bioavailable Formula for Increased Absorption | Made in the USA

What is NAD+ Complete?

NAD+ is a compound that's vital to life as we know it, used by every living cell in hundreds of biochemical functions. Stress and wear-and-tear on your body over time can deplete your NAD+ supply, and ultimately affect your overall health and well-being.

Some people swear by one NAD+ booster. Some companies want you to believe one is best. NAD+ Complete eliminates having to choose, with a 4-in-1 formula incorporating four studied NAD+ boosters—NMN, NR, trigonelline, and NAD+ itself—into one liposomal formula that helps protect the active ingredients through digestion to provide a more sustained release over time.

Use it consistently on its own to fuel cellular energy production, repair and recovery processes, and the resilience to help you stand up to the stressors of modern life. Or take it alongside your go-to NAD+ booster for added coverage and timed release.

Ingredients & Supplement Facts

Active Ingredients:

  • NMN (nicotinamide mononucleotide): 310mg
  • NAD+ (nicotinamide adenine dinucleotide): 160mg
  • NR (nicotinamide riboside): 100mg
  • Trigonelline: 70mg

Inactive Ingredients:

  • Vegetable Cellulose (capsule)
  • Sunflower Lecithin
  • Rice Flour
  • Microcrystalline Cellulose
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NMN Liposomal Capsules

$55.46

NAD+ Complete

$70.46

NAD+ COMPLETE

NAD+, NMN, NR & TRIGONELLINE CAPSULES LIPOSOMAL FOR INCREASED ABSORPTION

NICOTINAMIDE MONONUCLEOTIDE (NMN)


• Converts directly into vital NAD+ coenzyme
• Supports energy production for daily vitality
• Promotes DNA repair and anti‑aging benefits

LIPOSOMAL CAPSULE TECHNOLOGY


• Enables fast absorption with targeted delivery
• Shields active ingredients from digestive enzymes
• Transports compounds into bloodstream for max efficacy

  • BOOST


    Your body generates NAD+ from precursors like NMN, NR, and Trigonelline. Production naturally slows with age. This pathway replenishes raw cellular materials to sustain healthy NAD+ levels.

  • PROTECT


    More NAD+ offers limited benefit if your body rapidly depletes it. Age‑related enzymes such as CD38 consume NAD+ before cells can utilize it. This pathway preserves your built‑up NAD+ levels.

  • OPTIMIZE


    NAD+ powers your mitochondria, yet efficiency matters equally as supply. This pathway boosts sirtuin activity and mitochondrial function, helping cells maximize existing NAD+ resources.

  • REGENERATE


    Daily cellular damage creates constant demand for your NAD+ supply. This pathway supports restorative sleep‑time processes to clear accumulated cellular burden.

    Clinical Trial: Evaluating the Efficacy of Liposomal NMN

    double-blind, placebo-controlled clinical trial was conducted with 15 healthy men aged 40 and older to measure the effects of NMN supplementation. Participants were randomly assigned to one of three groups (5 per group) and took their assigned supplement daily after breakfast for four weeks.

    • Placebo Group: Maltodextrin (4g/day)
    • Standard NMN Group: Non-liposomal NMN (350 mg/day)
    • Liposomal NMN Group: Liposomal NMN (350 mg/day)

    Blood NAD+levels were measured at four time points:

    1. Before supplementation (baseline)2. One hour after the first dose3. After four weeks of daily supplementation4. Four weeks after stopping supplementationThis study design allowed researchers to assess not just how effectively each form of NMN raisedNAD+levels, but also how long those effects persisted after supplementation ended.

    Liposomal NMN Increased Blood NAD+ Levels By 84%

    After four weeks of supplementation, the Liposomal NMN Group exhibited an 84% increase in blood NAD+ levels, rising from 28.6 µM (baseline) to 52.5 µM.

    Although NAD+ levels declined four weeks after participants stopped supplementation, they remained elevated at 36 µM compared to the baseline of 28.6 µM.

    Encapsulated NMN Boosted NAD+ More Effectively Than Standard NMN

    Among all groups, Liposomal NMN produced the greatest increase inNAD+levels after four weeks, outperforming both Standard NMN and placebo.

    NAD+

    This central coenzyme is directly involved in redox reactions and serves as a substrate for energy production enzyme activity, including sirtuins and poly(ADP-ribose) polymerases (PARPs), which regulate cellular metabolism, DNA repair, and epigenetic modifications.

    NMN

    ThisNAD+precursor, which is directly converted toNAD+through the NMNAT enzyme in the Salvage Pathway, has been shown to effectively increase intracellularNAD+levels in numerous clinical trials, thereby enhancing mitochondrial function, energy production, and the activity ofNAD+-dependent enzymes.

    NR

    ThisNAD+precursor, which is converted toNAD+through the Preiss-Handler Pathway, has also demonstrated the ability to increaseNAD+levels in cells. It supports cellular repair mechanisms, particularly those involved in DNA damage response and oxidative stress mitigation. By buttressingNAD+levels, NR promotes the activation of sirtuins and PARPs, which protect genomic stability and regulating cellular metabolism.

    Trigonelline

    Trigonelline promotes cellularNAD+production differently than NMN or NR. This methylated form of niacin offers several advantages: exceptional stability in the bloodstream, slow release into target tissues, non-flushing, protection against stomach digestion, and directNAD+increase in muscle tissues.

    Liposomes Increase BioavailabilityWith our Liposomal products, approximately 90% of the payload reaches the bloodstream intact, regardless of what the payload is.

    For example, with our Liposomal Green Tea Extract around 90% of the EGCG reaches the bloodstream.

    With regular Green Tea extract, around 9% of EGCG reaches the bloodstream.

    Hence the study below shows it is about 10x more bioavailable.

    Regular Apigenin is around 30% bioavailable, so you can expect our Liposomal Apigenin to be approximately 3x more bioavailable than regular Apigenin.

    Although we don't have research on bioavailability of all our Liposomal products, below we show research that demonstrates increased bioavailability of 3 to 40x when using liposomes in some of the most popular supplements we produce.

    Purest Ingredients

    All our products are non-GMO and 100% free from preservatives, artificial colours, flavours and sweeteners.

    Advanced Testing

    We use pharmaceutical-grade testing procedures and our products have to pass through 4 rounds of testing.

    Certified Labs

    Our products are tested in ISO-Certified and cGMP certified labs for ultimate quality, purity and potency.

    Certifications

    Supported by Science

    Frequently Asked Questions

    What are the benefits of liposomal delivery? Are liposomes really better?

    When taken sublingually, approximately 30% of a 125 mg dose gets absorbed under the tongue, with the remainder being swallowed. At higher dosages, the % goes down, as the capillaries are full and have limited transport.

    A much greater % makes it to bloodstream with liposomal delivery. Liposomes also protect the payload from degradation once in the bloodstream.

    Lastly, Liposomes release the payload over a much longer period – up to 24 hours. This is better when taking larger dosages.

    The rapid delivery to the bloodstream with Sublingual can be an advantage when taking before exercise. The energy surge most users feel is also nice confirmation that it is doing something.

    What are the liquid and powdered liposome differences in bioavailability and stability?

    Our liquid and powdered liposomes have approximately the same availability in the bloodstream, but the powdered liposomes release the payload more slowly over 24 hours. We don’t know if that makes it more effective than a faster release.

    Powdered liposomal products have a shelf life of over two years, rather than the 12 months or so for liquid liposomal products when stored at room temp.

    What's the difference between Liposomal vs. Delayed & Extended Release Caps?

    Delayed Release & Extended Release Caps protect ingredients from stomach acid only. They delay, but don't really sustain ingredient release.

    Liposomes protect the payload through the GI tract and into the bloodstream, then release more slowly up to 24 hours (depending on the liposome).

    In addition to a big increase in bioavailability, they are truly sustained release. Any supplement known to have poor bioavailability should use liposomal delivery.

    Are any of your liposomal products heat-sensitive?

    The liposomal powder capsule products are not heat sensitive.

    The liposomal gels however should not be exposed to heat exceeding 115 degrees Fahrenheit for more than a few days. Liposomes break down a bit when exposed to extended periods of high heat.

    Shop Our Best Sellers

    NMN Liposomal Capsules

    $55.46

    NAD+ Complete

    $70.46